A/Prof Maija Kohonen-Corish
Microbiome Research Centre, St George & Sutherland Clinical School, UNSW Sydney
Associate Professor Kohonen-Corish completed her undergraduate studies in Finland at University of Helsinki and then PhD in human genetics at John Curtin School of Medical Research in Canberra. Her cancer genetics laboratory at the John Curtin School was one of the first in Australia to study the molecular basis of Lynch Syndrome. She moved to Garvan Institute of Medical Research in Sydney in 2002 where she established a translational molecular biology research program in colorectal and lung cancer. Her team identified new tumour suppressor genes and biomarkers in patient tumours and developed a drug-induced model of proximal colon cancer, using the new MCC-knockout mouse and other gene knockout strains. They found that the MCC gene is frequently silenced in colorectal polyps and cancer through promoter methylation and discovered its molecular functions in cell-cell adhesion and DNA repair. She joined the Microbiome Research Centre at UNSW Sydney in 2018 to study the human microbiome in cancer and its impact on therapy responsiveness. She is a member of the InSiGHT Variant Interpretation Committee for the DNA mismatch repair genes in Lynch Syndrome.
(Sat 13:30:15-00:00 Eston Room) Session 1: Welcome Plenary
(14:50-15:00) GRW041 — Mouse Model of Mcc Gene Deletion Reveals Novel Pathways in Colitis & Cancer
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